Centers of Excellence in Chemical Methodologies and Library Development

The summary for the Centers of Excellence in Chemical Methodologies and Library Development grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Centers of Excellence in Chemical Methodologies and Library Development: The purpose of this RFA is to reannounce and to update the National Institute of General Medical Sciences (NIGMS) program of "Centers of Excellence in Chemical Methodologies and Library Development" (CMLD Centers), last issued as RFA-GM-01-006 in June 2001. The goal of this program is to stimulate the establishment of multi- investigator research centers whose mission will be to develop efficient, general, state-of-the-art methodologies for the design, synthesis, analysis, and handling of chemical diversity libraries. The CMLD Centers will feature collaborations and team approaches that otherwise would not be established, including individuals from various subdisciplines within the field of chemistry and/or from cognate fields, that will develop novel enabling methodologies. Each Center will establish a library synthesis core facility that will serve two purposes. First, the library synthesis core will validate newly-developed methodologies for application to diversity-oriented synthesis (also known as combinatorial chemistry). Second, the library synthesis core will apply newly-developed chemical methodologies and strategies to the generation of chemical diversity libraries for high- throughput biological screening. This will provide "real world" tests of the utility of new methodologies and will also facilitate the study of complex biological phenomena. Each Center must develop a plan for outreach to the biology research community. The essential goals of the CMLD Centers program are to discover and to implement fundamental new chemistry that will facilitate access to high-quality libraries of expanded diversity.