Deep Sequencing and Haplotype Profiling of Mental Disorders (R01)

The summary for the Deep Sequencing and Haplotype Profiling of Mental Disorders (R01) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.
Deep Sequencing and Haplotype Profiling of Mental Disorders (R01): Purpose. With the initial stages of the Human Genome Project completed and new insights gained into the complex interplay of genomic function, genomic structure and the environment in mental disorders, attention is shifting towards the translational promise of the completed human sequence and a new era of genomic medicine in mental disorders. However, there are still major obstacles that need to be addressed before this occurs. It will be necessary to see a confluence of developments in genomic technologies and epidemiological methods, such as high throughput sequencing of candidate genes or genomic regions; global single nucleotide polymorphism (SNP) or haplotype analysis; improved measurements of environmental factors; well-characterized clinical phenotypes and endophenotypes; and the development of new analytical approaches. Furthermore, these advances will have to be applied in carefully crafted study designs and, implicitly, in large samples. A special emphasis of this Funding Opportunity Announcement (FOA) issued by the National Institute of Mental Health (NIMH), National Institutes of Health (NIH), is to support applications that implement large-scale studies and innovative analytical designs that will disaggregate a given mental disorder into components of finite risks. These developments may be evolutionary or may be fundamentally new and may lead to paradigm shifts in the field. Applications submitted in response to this FOA may propose new technologies for cost effective whole genome analysis and in-depth sequencing and analysis of candidate genes and genomic regions in pedigrees or in a sample of unrelated cases with mental disorders. Applications for large-scale haplotype analysis and the development of new analytical methods also are encouraged. Projects funded under this funding opportunity will focus on phenotypically well-characterized samples from the NIMH Human Genetics Initiative (http://nimhgenetics.org/) but may also use existing sample collections not included in the repository and study one of seven mental disorders: anorexia nervosa, attention deficit hyperactivity disorder, autism and related autism spectrum disorders, depression, bipolar disorder, obsessive compulsive disorder and schizophrenia. To take into account the rapid technological and scientific developments now occurring in genetics, applications funded under this FOA will be limited to a three-year period. Results from research funded under this funding opportunity will have direct implications for diagnosis, treatment, and, ultimately, prevention of mental disorders.
Federal Grant Title: Deep Sequencing and Haplotype Profiling of Mental Disorders (R01)
Federal Agency Name: National Institutes of Health
Grant Categories: Health
Type of Opportunity: Discretionary
Funding Opportunity Number: PA-07-209
Type of Funding: Grant
CFDA Numbers: 93.242
CFDA Descriptions: Mental Health Research Grants
Current Application Deadline: No deadline provided
Original Application Deadline: Multiple Receipt Dates - See Link to Full Announce
Posted Date: Dec 20, 2006
Creation Date: Dec 20, 2006
Archive Date: Apr 05, 2008
Total Program Funding:
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching: No
Applicants Eligible for this Grant
Others (see text field entitled "Additional Information on Eligibility" for clarification) Native American tribal governments (Federally recognized) County governments Public and State controlled institutions of higher education Small businesses Public housing authorities/Indian housing authorities Independent school districts State governments Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments)
Additional Information on Eligibility
Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply.
Link to Full Grant Announcement
Information not provided
Grant Announcement Contact
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV
FBOWebmaster@OD.NIH.GOV If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
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