Engineering Biological and Biomedical Systems (EBBS)

The summary for the Engineering Biological and Biomedical Systems (EBBS) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the U.S. National Science Foundation, which is the U.S. government agency offering this grant.
Engineering Biological and Biomedical Systems (EBBS): TheEngineering Biological and Biomedical Systems(EBBS)program expandsour understanding of biological and physiological systems,andithelpsimprove humanhealth.ForU.S.leadershipin biotechnology,theengineeringofbiologyisrequiredat every scale.Engineering is needed forsensingbiomarkerstomakingproteinsto restoring functions of the body.InEBBS,fundamentalmechanistic insightsarecombinedwith experimental and computational techniques.Thisapproachhelpsdevelopplatforms, devices, organisms, tissues,andprocesses thatbringnewunderstanding and control of biological functions. EBBSsupportsstudies of mechanismsthatdrivethe behavior of microbial populations and cells,and of therapeutic cells and tissues.This includes discovering theunderlying engineering principlesthat are needed tocapturethe responses of biological systems and bioreactors.It alsoincludesthecreationofnovelbiosensing platformsandnew optical imaging and modulation strategies.Research that enables the design of biological systems to sense and respond to novel stimuli is welcome. Similarly, projects leading to insight intotissuechangesor injury,andtosystems thatimitateor restorethefunctionsoftissuesororgans areencouraged. Projects thatadvancerehabilitation engineeringthrough new theories and approaches are supported by the EBBS program. Fundamental engineering research driven by theneeds of persons with disabilitiesis encouraged. The EBBS programexpandswhat is possible inbiomanufacturing;researchmayadvancebiotechnology and/orhealth.EBBSresearchmustenableimprovedbiological processes,createnovelbiomedical technologies, orachievenewunderstanding of physiological or pathological processes. EBBSdoesnot support proposalswithamaingoal ofdrug design,drugdelivery, or the development of animal models of disease.Usingexisting models for experimental testing and validation is acceptable. Projectsthatfocus ontesting andvalidatingtherapiesare not supported.Clinical trials are not supported.Limitedstudies involving human volunteers may be supported ifappropriate tothe projectobjectives. Projects focused on commercialization are moreappropriate fortheNSFDirectorate for Technology, Innovation, and Partnerships (TIP). Partnerships:Tospeeddiscovery and innovation, NSF partners with federal agencies, industry, internationalgroups, and others. Current opportunities are atNSF ENG Partnerships.
Federal Grant Title: Engineering Biological and Biomedical Systems (EBBS)
Federal Agency Name: U.S. National Science Foundation (NSF)
Grant Categories: Science and Technology and other Research and Development
Type of Opportunity: Discretionary
Funding Opportunity Number: PD-26-369Y
Type of Funding: Grant
CFDA Numbers: 47.041
CFDA Descriptions: Information not provided
Current Application Deadline: May 26th, 2026
Original Application Deadline: May 26th, 2026
Posted Date: April 24th, 2026
Creation Date: April 24th, 2026
Archive Date: June 25th, 2026
Total Program Funding:
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching: No
Last Updated: April 24th, 2026
Applicants Eligible for this Grant
Unrestricted (i.e., open to any type of entity below), subject to any clarification in text field entitled "Additional Information on Eligibility"
Link to Full Grant Announcement
NSF Program Desccription PD-26-369Y
Grant Announcement Contact
NSF grants.gov support
[email protected]
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