NIH Research Program Projects (Parent P01 Clinical Trial Optional)

The summary for the NIH Research Program Projects (Parent P01 Clinical Trial Optional) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

NIH Research Program Projects (Parent P01 Clinical Trial Optional): Through this Notice of Funding Opportunity (NOFO), the participating NIH Institutes, Centers, and Offices (ICOs) invite applications for the investigator-initiated Program Project (P01). A P01 supports a broadly based, multidisciplinary research program with a specific major scientific objective or theme. The proposed Program Projects are focused on the programmatic interests of one or more of the participating ICOs based on their scientific missions. A program project utilizes research projects with a common central scientific theme, an administrative core, and optional shared resource core(s) to accomplish ICOs' programmatic objectives.

Federal Grant Title:	NIH Research Program Projects (Parent P01 Clinical Trial Optional)
Federal Agency Name:	National Institutes of Health (HHS-NIH11)
Grant Categories:	Health
Type of Opportunity:	Discretionary
Funding Opportunity Number:	PA-27-061
Type of Funding:	Grant
CFDA Numbers:	93.113, 93.172, 93.233, 93.273, 93.279, 93.307, 93.313, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.855, 93.866, 93.879
CFDA Descriptions:	Information not provided
Current Application Deadline:	May 25th, 2029
Original Application Deadline:	May 25th, 2029
Posted Date:	October 14th, 2026
Creation Date:	October 14th, 2026
Archive Date:	July 25th, 2029
Total Program Funding:
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching:	No
Last Updated:	October 14th, 2026

Applicants Eligible for this Grant: State governments - County governments - City or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For-profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification.)
Additional Information on Eligibility: Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Grant Announcement Contact: Referral Officer
Email: [email protected]
National Cancer Institute (NCI)
Similar Government Grants: • Early-Onset Cancers: Investigating Etiology, Mechanisms, and Early Detection Strategies (R...; • Lasker Clinical Research Scholar's Program (Si2/R00 Clinical Trial Optional); • Institutional Mentored Career Development Award (Parent K12) (Clinical Trials Not Allowed); • Predoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed); • HEAL Initiative: Limited Competition for the HEALthy Brain and Child Development (HBCD) St...; • Outstanding New Environmental Scientist Award (ONES); • Environmental Health Sciences Core Center Grants; • Leiomyomata Uteri: Basic Science and Translational Research
More Grants from the National Institutes of Health: • Early-Onset Cancers: Investigating Etiology, Mechanisms, and Early Detection Strategies (R...; • Collaborative Program Grant for Interdisciplinary Teams (RM1 Clinical Trial Optional); • Palliative Care Research Across the Lifespan: Leveraging the Palliative Care Consortium (R...; • Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2027, 2028...; • Accelerating Research and Development of Next Generation Vaccines against Malaria - a Mode...