Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)

The summary for the Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional): The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs).Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting clinical research projects in collaboration with NIH intramural investigators.

Federal Grant Title:	Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)
Federal Agency Name:	National Institutes of Health (HHS-NIH11)
Grant Categories:	Health
Type of Opportunity:	Discretionary
Funding Opportunity Number:	PAR-26-116
Type of Funding:	Cooperative Agreement
CFDA Numbers:	93.313
CFDA Descriptions:	Information not provided
Current Application Deadline:	March 6th, 2027
Original Application Deadline:	March 6th, 2027
Posted Date:	December 8th, 2025
Creation Date:	December 8th, 2025
Archive Date:	April 10th, 2027
Total Program Funding:
Maximum Federal Grant Award:	$500,000
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching:	No
Last Updated:	December 8th, 2025

Applicants Eligible for this Grant: State governments - County governments - City or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For-profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification.)
Additional Information on Eligibility: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.
Grant Announcement Contact: David J. Eckstein, PhD
[email protected]
[email protected]
Similar Government Grants: • Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Preg...; • NINR Resources and Related Research Projects in Firearm Injury Prevention (R24 Clinical Tr...; • Advanced-Stage Development and Utilization of Research Infrastructure for Interdisciplinar...; • Research Infrastructure Development for Interdisciplinary Aging Studies (R61/R33 - Clinica...; • Advancing Health Equity through Interventions to Prevent and Address Housing Instability (...; • Limited Competition of the MAPP Research Network(U01); • Prevention of Lower Urinary Tract Symptoms in Women: Bladder Health Scientific and Data Co...; • Prevention of Lower Urinary Tract Symptoms in Women: Bladder Health Clinical Centers (PLUS...
More Grants from the National Institutes of Health: • Single Source Renewal for the Continuation of the Liver Cirrhosis Network: Scientific and ...; • NIGMS Institutional Biomedical Undergraduate Research Training (BURT) Program (T34); • Limited Competition: Outcomes of Electronic Medical Records and Genomics (eMERGE) Genomic ...; • Maximizing Investigators' Research Award (MIRA) (R35 - Clinical Trial Optional); • Institutional Network Award for Promoting Kidney, Urologic, and Hematologic Research Train...