Science of Behavior Change: Assay Development and Validation for Self-Regulation Targets (UH2/UH3)

The summary for the Science of Behavior Change: Assay Development and Validation for Self-Regulation Targets (UH2/UH3) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.
Science of Behavior Change: Assay Development and Validation for Self-Regulation Targets (UH2/UH3): This initiative is funded through the NIH Common Fund, which supports cross-cutting programs that are expected to have exceptionally high impact. All Common Fund initiatives invite investigators to develop bold, innovative, and often risky approaches to address problems that may seem intractable or to seize new opportunities that offer the potential for rapid progress.

This Phased Innovation Awards Cooperative Agreement Funding Opportunity Announcement (FOA) solicits applications to support a collaborative research infrastructure involving an interdisciplinary team of basic and clinical scientists to develop the foundation for an experimental medicine approach to behavior change. Research supported by this FOA is meant to support activities focused on behavior change targets in the domain of self-regulation through four main target validation steps:

1. Identify a set of putative targets within the self-regulation domain that are implicated in medical regimen adherence and at least one other health behavior;

2. Leverage existing or develop new experimental or intervention approaches to engage identified targets;

3. Identify or develop appropriate assays (measures) to permit verification of target engagement;

4. Test the degree to which engaging identified targets produces a desired change in medical regimen adherence and at least one other health behavior. While testing target engagement in specific clinical samples is permitted, the targets identified and the behavior change outcomes measured should be selected based on their hypothesized relevance to at least two clinical endpoints or disease conditions.

Funds from the NIH will be made available through the UH2/UH3 Phased Innovation Awards Cooperative Agreement mechanism.The initial UH2 phase will support steps 1-3 above. UH2 projects that have met their objectives and agreed upon milestones will be administratively considered by NIH and prioritized for transition to the UH3 validation phase to complete step 4 above. Projects proposed in response to this FOA will require multidisciplinary efforts and therefore all applicant teams must include expertise in basic and clinical science. Investigators responding to this FOA must address both UH2 and UH3 phases.

The output of these UH2/UH3 Target Validation Projects, to be facilitated by a Resource and Coordinating Center (RCC) funded under a companion FOA RFA-RM-14-017, will be a toolkit of validated and documented assays of specific targets in the domain of self-regulation, and experimental manipulations/interventions that engage those targets.

Please refer to the Science of Behavior Change (SOBC) website regularly for updates, frequently asked questions (FAQs), and other announcements related to this FOA and the companion FOAs.

SOBC Website: http://www.commonfund.nih.gov/behaviorchange/

FAQs: http://commonfund.nih.gov/behaviorchange/faq/
Federal Grant Title: Science of Behavior Change: Assay Development and Validation for Self-Regulation Targets (UH2/UH3)
Federal Agency Name: National Institutes of Health
Grant Categories: Health
Type of Opportunity: Discretionary
Funding Opportunity Number: RFA-RM-14-020
Type of Funding: Cooperative Agreement
CFDA Numbers: 93.310
CFDA Descriptions: Trans-NIH Research Support
Current Application Deadline: Mar 20, 2015
Original Application Deadline: Mar 20, 2015
Posted Date: Jan 8, 2015
Creation Date: Jan 8, 2015
Archive Date: Apr 20, 2015
Total Program Funding:
Maximum Federal Grant Award: none
Minimum Federal Grant Award: none
Expected Number of Awards:
Cost Sharing or Matching: No
Applicants Eligible for this Grant
Native American tribal organizations (other than Federally recognized tribal governments)
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Special district governments
Private institutions of higher education
State governments
City or township governments
Native American tribal governments (Federally recognized)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
County governments
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Public housing authorities/Indian housing authorities
For profit organizations other than small businesses
Small businesses
Independent school districts
Public and State controlled institutions of higher education
Additional Information on Eligibility
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Link to Full Grant Announcement
http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-14-020.html
Grant Announcement Contact
NIH OER Webmaster [email protected]
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster

National Institutes of Health 301-496-3405
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