Single Source: HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Data Translation Center (U54 Clinical Trial Optional)

The summary for the Single Source: HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Data Translation Center (U54 Clinical Trial Optional) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Single Source: HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Data Translation Center (U54 Clinical Trial Optional): This is a Notice of Funding Opportunity (NOFO) for a Single Source that will invites an application from an eligible organization to apply. Please see Section III. Eligibility for additional information. The NHLBI is announcing its intent to issue a single source cooperative agreement to Northwestern University. This NOFO solicits a renewal of the Data Translation Center for an ongoing NHLBI phenomics program, HeartShare, to coordinate the overall project, continue to oversee enrollment of a cohort of patients with heart failure with preserved ejection fraction (HFpEF), curate and analyze prospective deep phenotyping data, and support planning, implementation, and data analysis for clinical trials. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered.Companion NOFO RFA-HL-27-008 will support Clinical Centers for recruitment and follow-up of heart failure patients and a Clinical Trial Center for new clinical trial activities.

Federal Grant Title:	Single Source: HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Data Translation Center (U54 Clinical Trial Optional)
Federal Agency Name:	National Institutes of Health (HHS-NIH11)
Grant Categories:	Health
Type of Opportunity:	Discretionary
Funding Opportunity Number:	RFA-HL-27-009
Type of Funding:	Cooperative Agreement
CFDA Numbers:	93.837
CFDA Descriptions:	Information not provided
Current Application Deadline:	July 9th, 2026
Original Application Deadline:	July 9th, 2026
Posted Date:	May 19th, 2026
Creation Date:	May 19th, 2026
Archive Date:	September 7th, 2026
Total Program Funding:
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching:	No
Last Updated:	May 19th, 2026

Applicants Eligible for this Grant: State governments - County governments - City or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For-profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification.)
Additional Information on Eligibility: Refer to Section III. Eligibility Information in the NOFO for additional information on eligibilityThis is a non-competitive funding opportunity intended, if the peer-reviewed application is meritorious, to fund a single award. Only the following applicant is eligible to apply for this single source funding: Northwestern University.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Grant Announcement Contact: Division of Cardiovascular Sciences, HeartShare Team
[email protected]
Division of Cardiovascular Sciences, HeartShare Team
Similar Government Grants: • HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Cli...; • Stimulating Access to Research in Residency (StARR) (R38 Independent Clinical Trial Not Al...; • Single Source: Bench to Bassinet Congenital Heart disease Advancing New understanding in G...; • Phased Multi-Site Clinical Trial: Testing Prevention of Cardiovascular Disease in Young Ad...; • Phased Multi-Site Clinical Trial: Testing Prevention of Cardiovascular Disease in Young Ad...; • The Relationship Between Hypertension and Inflammation; • Community-Responsive Interventions to Reduce Cardiovascular Risk in American Indians and A...; • Weight Loss in Obese Adults with Cardiovascular Risk Factors: Clinical Interventions (U01)
More Grants from the National Institutes of Health: • Implementation Science to Advance HIV Prevention, Treatment, and Care (R61/R33 Clinical Tr...; • HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR...; • HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR...; • Centers for Structural Biology of HIV and Other Infectious Diseases (U54 Clinical Trial No...; • BRAIN Initiative: Research Opportunities Using Invasive Neural Recording and Stimulating T...