The Early Detection Research Network: Biomarker Reference Laboratories

The summary for the The Early Detection Research Network: Biomarker Reference Laboratories grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.
The Early Detection Research Network: Biomarker Reference Laboratories: The Division of Cancer Prevention (DCP), National Cancer Institute (NCI), invites new and competing renewal cooperative agreement applications to continue the national Network that has the responsibility for the development, evaluation, and validation of biomarkers for earlier cancer detection and risk assessment. Biomarkers are defined as cellular, biochemical, and molecular (genetic and epigenetic) alterations by which a normal or abnormal, biologic process can be recognized or monitored. Biomarkers are measurable in biological media, such as in tissues, cells, or fluids. The Network has four main components: Biomarker Developmental Laboratories (BDLs), Biomarker Reference Laboratories (BRLs) (formerly known as Biomarker Validation Laboratories), Clinical Epidemiology and Validation Centers (CECs)(formerly known as Clinical and Epidemiologic Centers), and a Data Management and Coordinating Center (DMCC). The BDLs have responsibility for the development and characterization of new or the refinement of existing biomarkers and assays. The BRLs serve as a Network resource for clinical and laboratory validation of biomarkers, which include technological development and refinement. The CECs collaboratively conduct clinical and epidemiological research on the Network-wide clinical validation of biomarkers. The DMCC supports statistical and computational analysis and informatics infrastructure and coordinates network-wide meetings and conferences. For further details, see The Early Detection Research Network (EDRN) Steering Committee (SC) is composed of the Principal Investigators (PIs) in the Network and appropriate NCI staff to coordinate the work of the Network. The purpose of this Request for Applications (RFA) (CA-05-009) is to invite new and competing renewal applications for the BRLs. An RFA (CA-04-006) for the BDLs was previously published in the NIH guide, September 26, 2003. This RFA is available at The RFA for the CEC (CA-05-005) was published in the NIH Guide on January 14, 2004 and is available at The RFA for the DMCC is being issued at a later date. Applicants are encouraged to seek funding to participate in more than one component, because it is recognized that collaborations already exist in individual institutions for clinical testing and validation of biomarkers and reagents.
Federal Grant Title: The Early Detection Research Network: Biomarker Reference Laboratories
Federal Agency Name: National Institutes of Health
Grant Categories: Health Education
Type of Opportunity: Discretionary
Funding Opportunity Number: RFA-CA-05-009
Type of Funding: Cooperative Agreement
CFDA Numbers: 93.394
CFDA Descriptions: Cancer Detection and Diagnosis Research
Current Application Deadline: No deadline provided
Original Application Deadline: Aug 16, 2004
Posted Date: Apr 12, 2004
Creation Date: Apr 12, 2004
Archive Date: Oct 14, 2004
Total Program Funding:
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching: No
Applicants Eligible for this Grant
State governments County governments City or township governments Special district governments Independent school districts Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Small businesses Others (see text field entitled "Additional Information on Eligibility" for clarification)
Link to Full Grant Announcement
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