Division of Molecular and Cellular Biosciences Core Programs

The summary for the Division of Molecular and Cellular Biosciences Core Programs grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Science Foundation, which is the U.S. government agency offering this grant.
Division of Molecular and Cellular Biosciences Core Programs: MCB supports research that promises to uncover the fundamental properties of living systems across atomic, molecular, subcellular, and cellular scales. The program gives high priority to projects that advance mechanistic understanding of the structure, function, and evolution of molecular, subcellular, and cellular systems, especially research that aims at quantitative and predictive knowledge of complex behavior and emergent properties. MCB encourages research exploring new concepts in molecular and cellular biology, while incorporating insights and approaches from other scientific disciplines, such as chemistry, computer science, engineering, mathematics, and physics, to illuminate principles that govern life at the molecular and cellular level. MCB also encourages research that exploits experimental and theoretical approaches and utilizes a diverse spectrum of model and non-model animals, plants, and microbes across the tree of life. Proposals that pursue potentially transformative ideas are welcome, even if these entail higher risk. This solicitation calls for proposals in research areas supported by the four MCB core clusters, including: (i) structure, dynamics, and function of biomolecules and supramolecular assemblies, especially under physiological conditions (Molecular Biophysics); (ii) organization, processing, expression, regulation, and evolution of genetic and epigenetic information (Genetic Mechanisms); (iii) cellular structure, properties, and function across broad spatiotemporal scales (Cellular Dynamics and Function); and (iv) systems and/or synthetic biology to study complex interactions through modeling or manipulation or design of living systems at the molecular-to-cellular scale (Systems and Synthetic Biology). All MCB clusters prioritize projects that integrate across scales, investigate molecular and cellular evolution, synergize experimental research with computational or mathematical modeling, and/or develop innovative, broadly applicable methods and technologies. Projects that bridge the intellectual edges between MCB clusters are welcome. Projects that integrate molecular and cellular biosciences with other subdisciplines of biology are also welcome through the new Integrative Research in Biology (IntBIO) track. MCB strives to achieve key goals laid out in the NSF Strategic Plan. Among these goals are: (i) to empower Science Technology, Engineering, and Mathematics (STEM) talent to fully participate in science and engineering; (ii) to enable creation of new knowledge by advancing the frontiers of research and enhancing research capability; and (iii) to benefit society through translation of knowledge into solutions. In line with these goals, MCB seeks to increase the diversity of individuals and institutions in the molecular and cellular biosciences community we support. Hence, to be competitive, proposers must be intentional regarding broadening participation in their projects through efforts to promote diversity, equity, and inclusion of individuals traditionally underrepresented in STEM and of types of institutions, such as Minority-serving Institutions (MSIs), Primarily Undergraduate Institutions (PUIs), two-year colleges, institutions in jurisdictions associated with the Established Program to Stimulate Competitive Research (EPSCoR), as well as major research institutions. Also aligned with the NSF Strategic Plan, MCB encourages basic research ideas that are inspired by curiosity and/or by their potential use for societal benefit, especially pertaining to pressing challenges such as, but not limited to climate change, clean energy, feeding the world sustainably, or health. With regard to health-related challenges, it should be noted that research using biomedical model systems to address questions of basic scientific interest is permissible. However, in accordance with the PAPPG,MCB does not normally support biological research on mechanisms of disease in humans, including on the etiology, diagnosis, or treatment of disease or disorder. Similarly, MCB does not normally support biological research to develop animal models of such conditions or testing of procedures for their treatment. Proposals motivated by such disease-related goals will be returned without review.
Federal Grant Title: Division of Molecular and Cellular Biosciences Core Programs
Federal Agency Name: National Science Foundation (NSF)
Grant Categories: Science and Technology
Type of Opportunity: Discretionary
Funding Opportunity Number: 23-548
Type of Funding: Grant
CFDA Numbers: 47.074
CFDA Descriptions: Information not provided
Current Application Deadline: January 20th, 2024
Original Application Deadline: January 20th, 2024
Posted Date: January 19th, 2023
Creation Date: January 19th, 2023
Archive Date: February 19th, 2024
Total Program Funding: $100,000,000
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching: No
Last Updated: January 22nd, 2023
Applicants Eligible for this Grant
Others (see text field entitled "Additional Information on Eligibility" for clarification.)
Additional Information on Eligibility
*Who May Submit Proposals: Proposals may only be submitted by the following: -Non-profit, non-academic organizations: Independent museums, observatories, research labs, professional societies and similar organizations in the U.S. associated with educational or research activities. -Institutions of Higher Education (IHEs) - Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the US, acting on behalf of their faculty members.Special Instructions for International Branch Campuses of US IHEs: If the proposal includes funding to be provided to an international branch campus of a US institution of higher education (including through use of subawards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus, and justify why the project activities cannot be performed at the US campus.
Link to Full Grant Announcement
NSF Publication 23-548
Grant Announcement Contact
NSF grants.gov support
If you have any problems linking to this funding announcement, please contact the email address above.
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