DoD Tuberous Sclerosis Research Pilot Clinical Trial Award

The summary for the DoD Tuberous Sclerosis Research Pilot Clinical Trial Award grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the Dept of the Army USAMRAA, which is the U.S. government agency offering this grant.
DoD Tuberous Sclerosis Research Pilot Clinical Trial Award: The mission of the TSCRP is to encourage innovative research aimed at understanding the pathogenesis and manifestations of TSC to improve the lives of individuals with TSC. Within this context, the FY13 TSCRP encourages applications that address one or more of these vital program Focus Areas: - Genetic, epigenetic, and non-genetic modifiers of TSC. - Preclinical models and therapeutic strategies (e.g., cytotoxic agents, combination therapies). - Biomarkers for early detection, prognosis, and prediction of treatment outcomes (such as serum markers, imaging, electrophysiology, prenatal testing, and pharmacogenetics). - Impact of TSC manifestations in adults (e.g., care management, age-specific pathogenesis, epidemiology, renal, reproductive issues, and lymphangioleiomyomatosis [LAM]). - Long-term benefits and effects of mTOR inhibitors or other agents. - Novel strategies for diagnosis, treatment, and prevention of TSC manifestations including those geared toward early identification and intervention. - Cellular and molecular mechanisms of TSC and LAM pathogenesis. - Causes and treatment of epilepsy in TSC. - Causes and treatment of TSC-associated neurocognitive disorders including cognitive impairment, and psychiatric, behavioral, and sleep disorders. The TSCRP Pilot Clinical Trial Award mechanism supports studies of interventions (e.g., device, drug, biologic, surgical procedure, rehabilitative modality, behavioral intervention, or other) with the potential to have a major impact on the treatment or management of TSC. Funding from this award mechanism must support a pilot study aimed at obtaining preliminary data to support the rationale and design of subsequent clinical trials. Examples of research topics include but are not limited to the following: - Studies to identify an appropriate population. - Studies to identify the dosage, duration, and/or delivery strategy of the intervention. - Studies to evaluate the feasibility of the intervention in TSC. - Studies to better understand efficacy and safety. Pilot clinical trials may include exploratory studies involving limited human exposure that produce diagnostic or therapeutic information (e.g., screening studies, microdose studies), toxicity studies of an intervention, and studies to determine the mechanism of action and side effects of an intervention.
Federal Grant Title: DoD Tuberous Sclerosis Research Pilot Clinical Trial Award
Federal Agency Name: Dept of the Army USAMRAA
Grant Categories: Regional Development
Type of Opportunity: Discretionary
Funding Opportunity Number: W81XWH-13-TSCRP-PCTA
Type of Funding: Cooperative Agreement Grant
CFDA Numbers: 12.420
CFDA Descriptions: Military Medical Research and Development
Current Application Deadline: Jul 11, 2013
Original Application Deadline: Jul 11, 2013
Posted Date: May 03, 2013
Creation Date: May 03, 2013
Archive Date: Aug 10, 2013
Total Program Funding: $640,000
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards: 2
Cost Sharing or Matching: No
Applicants Eligible for this Grant
Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Grant Announcement Contact
CDMRP Help Desk 301-682-5507 [email protected]
CDMRP Help Desk [[email protected] ]
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