Enhancing Cancer Genomic Best Practices through Education, Surveillance, and Policy

The summary for the Enhancing Cancer Genomic Best Practices through Education, Surveillance, and Policy grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the Centers for Disease Control and Prevention, which is the U.S. government agency offering this grant.
Enhancing Cancer Genomic Best Practices through Education, Surveillance, and Policy: This FOA will allow for the development or expansion of state-based programs to promote applications of evidence-based breast and ovarian cancer genomics best practices through education, surveillance, and policy/systems change. Activities will focus on Hereditary Breast and Ovarian Cancer, but may also include Lynch Syndrome. Several system, policy, provider, and individual level barriers make the appropriate identification and treatment of high risk individuals difficult and this FOA will support state efforts to address these barriers and impact breast and ovarian cancer incidence rates. Funded applicants will develop, enhance, and evaluate education, surveillance, and policy activities related to promotion of breast and ovarian cancer genomics. These activities should take advantage of collaborations between funded applicants and partners, both internal (e.g. cancer registry, comprehensive cancer) and external (e.g., academic medical centers, non-profits, clinical genetics sites). Expected outcomes include the improvement of public and provider knowledge of hereditary cancers, genetic counseling, genetic testing, and associated clinical services, the assessment of the burden of hereditary cancers and use of genetic counseling, genetic testing and associated clinical services, and the improvement in access to and coverage of genetic counseling, genetic testing and associated clinical services for high risk individuals. Women with breast cancer susceptibility 1 and 2 (BRCA1/2) gene mutations have a substantially higher breast and ovarian cancer risk than those without such mutations, with a cumulative risk of developing breast and ovarian cancer up to 57 percent and 40 percent respectively. Women with a personal or family cancer history indicative of a BRCA 1/2 mutation may benefit from genetic counseling and testing. For those who test positive, interventions including chemoprevention, enhanced surveillance or prophylactic mastectomy and oophorectomy can decrease breast cancer incidence and ovarian cancer incidence by up to 95% and 80%, respectively. The United States Preventive Services Task Force (USPSTF) and the National Comprehensive Cancer Network (NCCN), have evidence-based recommendations for genetic counseling and testing for hereditary breast and ovarian cancer. People with Lynch syndrome have a higher likelihood of developing colorectal and other (e.g., gastric, endometrial, and ovarian) cancers. The Evaluation of Genomic Applications in Practice and Prevention (EGAPP™) Working Group found sufficient evidence to recommend offering genetic testing for Lynch syndrome to individuals with newly diagnosed colorectal cancer to reduce morbidity and mortality in relatives.
Federal Grant Title: Enhancing Cancer Genomic Best Practices through Education, Surveillance, and Policy
Federal Agency Name: Centers for Disease Control and Prevention
Grant Categories: Health
Type of Opportunity: Discretionary
Funding Opportunity Number: CDC-RFA-DP14-1407
Type of Funding: Cooperative Agreement
CFDA Numbers: 93.283
CFDA Descriptions: Centers for Disease Control and Prevention_Investigations and Technical Assistance
Current Application Deadline: Jun 17, 2014 Dates: 1. Letter of Intent (LOI)
Original Application Deadline: Jun 17, 2014 Dates: 1. Letter of Intent (LOI)
Posted Date: May 2, 2014
Creation Date: May 2, 2014
Archive Date: Jul 17, 2014
Total Program Funding: $1,500,000
Maximum Federal Grant Award: $300,000
Minimum Federal Grant Award: $300,000
Expected Number of Awards: 5
Cost Sharing or Matching: No
Applicants Eligible for this Grant
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility
Eligibility Information

1. Eligible Applicants:

Government Organizations:

• State or their bona fide agents (includes the District of Columbia)
• Territorial governments or their bona fide agents in the Commonwealth of Puerto Rico and the Virgin Islands.

2. Special Eligibility Requirements:

All eligible applications will be initially reviewed for completeness by the Procurement and Grants Office (PGO) staff. In addition, eligible applications will be jointly reviewed for responsiveness by National Center for Chronic Disease Prevention and Health Promotion and PGO. Incomplete applications and applications that are non-responsive to the eligibility criteria will not advance through the review process. Applicants will be notified the application did not meet eligibility and/or published submission requirements.
Grant Announcement Contact
CDC Procurement and Grants Office (PGO) Technical Information Management Section (TIMS) Phone: 770-488-2700 E-mail: [email protected]
Technical Information Management Section (TIMS)

Centers for Disease Control and Prevention 770-488-2756
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