Identification of Alcohol Biomarker Signatures
The summary for the Identification of Alcohol Biomarker Signatures grant is detailed below.
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Identification of Alcohol Biomarker Signatures: This Request for Applications (RFA) fosters the utilization of genomic, proteomic, and metabolomic technologies for the development of diagnostic biomarker signatures for alcohol consumption and alcohol-induced tissue injury. Specifically, the research program is aimed at identifying signatures of acute and chronic alcohol consumption for diagnosing high-risk drinking, detecting relapse to drinking, disclosing recent drinking in high risk situations such as pregnancy, as well as signatures for alcohol-induced early tissue damage including brain damage, alcoholic liver disease (ALD), pancreatitis, immune disorders, cancer, cardiomyopathy and other alcohol-induced diseases. Recent advances in high-throughput technologies in genomics, proteomics, and metabolomics, in combination with robust bioinformatics enable researchers to rapidly survey thousands of differentially expressed genes, proteins, or metabolites simultaneously, thus employing an integrative! approach to identify unique biomarker signatures. These state-of-the-art technologies provide a great opportunity to discover a new generation of biomarkers. These signatures could lead to the identification of potential targets for medication development and for evaluating the efficacy of lead compounds in clinical trials. We encourage collaborations from disparate scientific areas and disciplines, including those not traditionally supported by NIAAA combining unique and complementary expertise, techniques, model systems and tissues. It is essential, however, that the proposed activities be within the mission of NIAAA.
Federal Grant Title: | Identification of Alcohol Biomarker Signatures |
Federal Agency Name: | National Institutes of Health |
Grant Categories: | Health |
Type of Opportunity: | Discretionary |
Funding Opportunity Number: | RFA-AA-06-002 |
Type of Funding: | Grant |
CFDA Numbers: | 93.273 |
CFDA Descriptions: | Alcohol Research Programs |
Current Application Deadline: | No deadline provided |
Original Application Deadline: | Jun 15, 2005 |
Posted Date: | Mar 23, 2005 |
Creation Date: | Mar 23, 2005 |
Archive Date: | Jul 15, 2005 |
Total Program Funding: | $2,000,000 |
Maximum Federal Grant Award: | |
Minimum Federal Grant Award: | |
Expected Number of Awards: | 6 |
Cost Sharing or Matching: | No |
- Applicants Eligible for this Grant
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses Public and State controlled institutions of higher education Private institutions of higher education State governments County governments City or township governments Special district governments Independent school districts Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled "Additional Information on Eligibility" for clarification)
- Additional Information on Eligibility
- Eligible agencies of the Federal Government are eligible to apply. Foreign institutions are not eligible to apply.
- Link to Full Grant Announcement
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