Systems Biology of Infection and Inflammation in Chronic Diseases (U19 Clinical Trial Not Allowed)

The summary for the Systems Biology of Infection and Inflammation in Chronic Diseases (U19 Clinical Trial Not Allowed) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

Systems Biology of Infection and Inflammation in Chronic Diseases (U19 Clinical Trial Not Allowed): The purpose of this notice of funding opportunity (NOFO) is to support the advancement of systems-level understanding of the link between infectious pathogens and inflammatory pathways that result in predisposition, onset and progression of chronic diseases. The NOFO will stimulate integration of clinical and patient data, large-scale omics datasets, advanced Artificial Intelligence (AI) and computational modeling to prevent, treat, and mitigate the combined impact of chronic diseases, inflammation, and infections.

Federal Grant Title:	Systems Biology of Infection and Inflammation in Chronic Diseases (U19 Clinical Trial Not Allowed)
Federal Agency Name:	National Institutes of Health (HHS-NIH11)
Grant Categories:	Health
Type of Opportunity:	Discretionary
Funding Opportunity Number:	RFA-AI-28-014
Type of Funding:	Cooperative Agreement
CFDA Numbers:	93.121, 93.172, 93.543, 93.8AM, 93.8RP, 93.8TD, 93.ADR, 93.AGR, 93.AR1, 93.DSS, 93.HL2
CFDA Descriptions:	Information not provided
Current Application Deadline:	February 18th, 2027
Original Application Deadline:	February 18th, 2027
Posted Date:	November 4th, 2026
Creation Date:	November 4th, 2026
Archive Date:	April 18th, 2027
Total Program Funding:	$26,000,000
Maximum Federal Grant Award:	$2,500,000
Minimum Federal Grant Award:
Expected Number of Awards:	10
Cost Sharing or Matching:	No
Last Updated:	November 4th, 2026

Applicants Eligible for this Grant: State governments - County governments - City or township governments - Special district governments - Independent school districts - Public and State controlled institutions of higher education - Native American tribal governments (Federally recognized) - Public housing authorities/Indian housing authorities - Native American tribal organizations (other than Federally recognized tribal governments) - Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education - Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education - Private institutions of higher education - For-profit organizations other than small businesses - Small businesses - Others (see text field entitled "Additional Information on Eligibility" for clarification.)
Additional Information on Eligibility: Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
Grant Announcement Contact: NIAID OGAT (Division of Microbiology and Infectious Diseases)
[email protected]
[email protected]
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