The Role of Neuronal/Glial Cell Interactions in Orofacial Pain Disorders

The summary for the The Role of Neuronal/Glial Cell Interactions in Orofacial Pain Disorders grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

The Role of Neuronal/Glial Cell Interactions in Orofacial Pain Disorders: - The goal of this initiative is to stimulate basic research on the role of glial cells in pain disorders of the orofacial complex and in particular, studies on the interactions between glial cells and neurons that lead to pathological pain states. This initiative will encourage molecular, cellular, and animal studies on 1) the mechanisms by which stimulation of primary afferent nociceptors (neurons) lead to activation of spinal cord, brain, and peripheral glial cells; 2) the influence of activated glial cells (astrocytes and microglia) on nociceptive neuron function in experimental pain models; 3) the identification of glial cell proteins and signaling pathways important in maintaining chronic pain states; 4) the identification of the neuronal proteins and signaling systems regulated by activated glial cells; and 5) the role of activated microglia as antigen presenting cells influencing systemic immune cell interactions with the CNS. The knowledge gai! ned from these approaches will lead to rapid and new advances in the identification analgesic targets for chronic pain disorders. - The total amount to be awarded is $2,000,000. - The anticipated number of awards is eight (8) to ten (10). - The types of mechanisms will include R01 and R21 grants. - Eligible organizations include: - For-profit organizations - Non-profit organizations - Public or private institutions, such as universities, colleges, hospitals, and laboratories - Units of State government - Units of local government - Eligible agencies of the Federal government - Foreign Institutions - Domestic Institutions - Faith-based or community-based organizations - Applicants may submit more than one application, provided they are scientifically distinct. - See Section IV.1 for application materials. - Telecommunications for the hearing impaired is available at: TTY 301-451-0088

Federal Grant Title:	The Role of Neuronal/Glial Cell Interactions in Orofacial Pain Disorders
Federal Agency Name:	National Institutes of Health
Grant Categories:	Health
Type of Opportunity:	Discretionary
Funding Opportunity Number:	RFA-DE-06-005
Type of Funding:	Grant
CFDA Numbers:	93.121
CFDA Descriptions:	Oral Diseases and Disorders Research
Current Application Deadline:	No deadline provided
Original Application Deadline:	Nov 17, 2005
Posted Date:	May 10, 2005
Creation Date:	May 10, 2005
Archive Date:	Dec 17, 2005
Total Program Funding:	$2,000,000
Maximum Federal Grant Award:
Minimum Federal Grant Award:
Expected Number of Awards:	8
Cost Sharing or Matching:	No

Applicants Eligible for this Grant: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses Public and State controlled institutions of higher education Private institutions of higher education State governments County governments City or township governments Special district governments Independent school districts Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility: Eligible agencies of the Federal Government are eligible to apply. Foreign institutions are eligible to apply.
Link to Full Grant Announcement: Information not provided
Grant Announcement Contact: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster [email protected] NIH OER Webmaster
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