HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

The summary for the HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional) grant is detailed below. This summary states who is eligible for the grant, how much grant money will be awarded, current and past deadlines, Catalog of Federal Domestic Assistance (CFDA) numbers, and a sampling of similar government grants. Verify the accuracy of the data FederalGrants.com provides by visiting the webpage noted in the Link to Full Announcement section or by contacting the appropriate person listed as the Grant Announcement Contact. If any section is incomplete, please visit the website for the National Institutes of Health, which is the U.S. government agency offering this grant.

HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional): The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects.

Federal Grant Title:	HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)
Federal Agency Name:	National Institutes of Health (HHS-NIH11)
Grant Categories:	Health, Income Security and Social Services
Type of Opportunity:	Discretionary
Funding Opportunity Number:	RFA-AT-25-003
Type of Funding:	Grant
CFDA Numbers:	93.121, 93.213, 93.273, 93.846, 93.853, 93.865, 93.866
CFDA Descriptions:	Information not provided
Current Application Deadline:	November 23rd, 2026
Original Application Deadline:	November 23rd, 2026
Posted Date:	January 8th, 2025
Creation Date:	January 8th, 2025
Archive Date:	December 29th, 2026
Total Program Funding:
Maximum Federal Grant Award:	$375,000
Minimum Federal Grant Award:
Expected Number of Awards:
Cost Sharing or Matching:	No
Last Updated:	January 8th, 2025

Applicants Eligible for this Grant: Public and State controlled institutions of higher education - Private institutions of higher education - Others (see text field entitled "Additional Information on Eligibility" for clarification.)
Additional Information on Eligibility: Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs) ; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Link to Full Grant Announcement: https://grants.nih.gov/grants/guide/rfa-files/RFA-AT-25-003.html
Grant Announcement Contact: NIH Grants Information
[email protected]
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
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